Anti-CADM-140 Antibody-positive Juvenile Dermatomyositis with Rapidly Progressive Interstitial Lung Disease and Cardiac Involvement
نویسندگان
چکیده
منابع مشابه
Anti-CADM-140/MDA5 antibody and clinical subsets of dermatomyositis
The clinical features of dermatomyositis (DM) have a close relationship with myositis-specific antibodies. Clinically amyopathic dermatomyositis (CADM) is a subgroup of DM, which manifests as characteristic skin symptoms compatible with DM, such as Gottron's sign and heliotrope rash with no or mild muscle symptoms. Sometimes, a life-threatening rapidly progressing interstitial lung disease can ...
متن کاملAnti-Ro 52 positive dermatomyositis presenting as rapidly progressive interstitial lung disease.
Dermatomyositis is frequently accompanied by interstitial lung disease. This varies greatly in severity, from an asymptomatic imaging finding to a fatal rapidly progressive disease. We present a successfully treated case of rapidly progressive anti-Ro 52 positive dermatomyositis-related interstitial lung disease with accompanying images. A 48-year-old man presented with a 6-week history of dry ...
متن کاملClinical and laboratory features of fatal rapidly progressive interstitial lung disease associated with juvenile dermatomyositis.
OBJECTIVE Rapidly progressive interstitial lung disease (RP-ILD) is a rare but potentially fatal complication of JDM. The aim of this study was to establish markers for the prediction and early diagnosis of RP-ILD associated with JDM. METHODS The clinical records of 54 patients with JDM were retrospectively reviewed: 10 had RP-ILD (7 died, 3 survived), 19 had chronic ILD and 24 were without I...
متن کاملEffective Administration of Rituximab in Anti-MDA5 Antibody–Positive Dermatomyositis with Rapidly Progressive Interstitial Lung Disease and Refractory Cutaneous Involvement: A Case Report and Literature Review
We describe the case of a 48-year-old man with dermatomyositis (DM) who demonstrated rapidly progressive interstitial lung disease (RP-ILD) and refractory cutaneous involvement together with high levels of anti-melanoma differentiation-associated gene 5 antibody (anti-MDA5-Ab). Even after combination immunosuppressive therapy including a corticosteroid, cyclosporine A, and intravenous cyclophos...
متن کاملMyositis autoantibodies in Korean patients with inflammatory myositis: Anti-140-kDa polypeptide antibody is primarily associated with rapidly progressive interstitial lung disease independent of clinically amyopathic dermatomyositis
BACKGROUND To investigate the association between myositis autoantibodies and clinical subsets of inflammatory myositis in Korean patients. METHODS Immunoprecipitation was performed using the sera of classic polymyositis (PM) (n = 11) and dermatomyositis (DM) (n = 38) patients who met the Bohan and Peter criteria for definite inflammatory myositis. A panel of defined myositis autoantibodies w...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Rheumatology
سال: 2011
ISSN: 0315-162X,1499-2752
DOI: 10.3899/jrheum.101220